Guillain-Barré Syndrome as a paraneoplastic neurological disease of pulmonary adenocarcinoma and squamous cell carcinoma: A case report

We present the case of a 69-year-old male who presented with profound weakness in the extremities. Remarkably, he lacked any identifiable precipitating factors preceding the onset of his illness. However, a diagnosis of Guillain-Barré syndrome (GBS) was established based on typical clinical symptoms...

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Bibliographic Details
Published inActa neurologica Taiwanica Vol. 33(4); p. 201
Main Authors Lin, Zong-Han, Hoe, Zheng-Yu
Format Journal Article
LanguageEnglish
Published China (Republic : 1949- ) 30.12.2024
Subjects
Adenocarcinoma - complications
Adenocarcinoma of Lung - complications
Aged
Carcinoma, Squamous Cell - complications
Guillain-Barre Syndrome - complications
Guillain-Barre Syndrome - diagnosis
Humans
Lung Neoplasms - complications
Male
Paraneoplastic Syndromes - complications
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Summary:We present the case of a 69-year-old male who presented with profound weakness in the extremities. Remarkably, he lacked any identifiable precipitating factors preceding the onset of his illness. However, a diagnosis of Guillain-Barré syndrome (GBS) was established based on typical clinical symptoms, cerebrospinal fluid analysis, and neurological examination. During his hospitalization, an incidental discovery of lung cancer was made. Subsequent pathology confirmed adenocarcinoma and squamous cell carcinoma in the lungs. This case report serves to underscore the exceptional rarity of the simultaneous occurrence of lung cancer and GBS, renewing interest in investigating GBS as a potential paraneoplastic neurological syndrome. Keywords: Guillain-Barré syndrome, paraneoplastic neurological disease, pulmonary adenocarcinoma, squamous cell carcinoma.
ISSN:1028-768X