Neurovascular coupling responses and cognitive function: The impact of aging and the interventional effect of exercise

Aging is a natural process accompanied with a progressive deterioration of cognitive functions. With an aging population, more and more elderly people are suffering from cognitive impairment. Previous studies have paid more attention to the impact of inflammation and oxidative stress on cognitive fu...

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Bibliographic Details
Published inSheng li hsüeh pao Vol. 75; no. 6; p. 903
Main Authors He, Yi-Min, Wu, Chun-Li, Dong, Yu-Mo, Wu, Hua-Duo, Wang, Qian, Jiang, Ning
Format Journal Article
LanguageChinese
Published China 25.12.2023
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Summary:Aging is a natural process accompanied with a progressive deterioration of cognitive functions. With an aging population, more and more elderly people are suffering from cognitive impairment. Previous studies have paid more attention to the impact of inflammation and oxidative stress on cognitive function during aging. Recently, it has been discovered that neurovascular coupling (NVC), a mechanism regulating cerebral blood flow, may play a significant role in aging-related cognitive impairment. NVC responses regulate the supply of energy substances and oxygen during brain activity, which in turn enhances cognitive function. However, as people grow older, NVC responses gradually weaken, which may be one of the mechanisms underlying aging-induced cognitive impairment. Given the important role of NVC responses in the brain, it is necessary to search for intervention methods that can improve NVC responses and promote cognitive function. Exercise is an effective means to delay aging and improve cognitive function.
ISSN:0371-0874