Qualitative analysis of Gynostemma longipes for medicinal usage

The Qinling-Daba Mountains area is the main producing areas of Gynostemma longipes for medicinal usage, and samples of wild whole plants in Pingli, Shaanxi Province and Qingchuan, Sichuan Province were collected. The ultra-high performance liquid chromatography coupled with quadrupole time-of-flight...

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Bibliographic Details
Published inZhongguo zhongyao zazhi Vol. 46; no. 4; p. 951
Main Authors Zhang, Meng-Meng, Zheng, Wei, Zhang, Jie, Gao, Lin, Liu, Xue-Feng, Luo, Ding-Qiang, Guo, Bao-Lin, Ma, Bai-Ping
Format Journal Article
LanguageChinese
Published China 01.02.2021
Subjects
Chromatography, High Pressure Liquid
Drugs, Chinese Herbal
Gynostemma
Mass Spectrometry
Saponins
component composition
medical usage
triterpenoid saponin
LC-MS analysis
Gynostemma longipes
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Summary:The Qinling-Daba Mountains area is the main producing areas of Gynostemma longipes for medicinal usage, and samples of wild whole plants in Pingli, Shaanxi Province and Qingchuan, Sichuan Province were collected. The ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(UHPLC-Q-TOF-MS~E) was used to profile the chemical compositions and analyze the similarities and differences of G. longipes samples in these areas. Based on the accurate molecular weight and fragment information obtained from Q-TOF-MS~E, the structures of the main components were identified by combining with the mass spectra, chromatographic behaviors of reference standards and related literatures. The results showed that the components of wild G. longipes from different places among Qinling-Daba Mountains area were similar. Forty-five chemical components were identified in the whole plant of G. longipes from Pingli, Shaanxi Province, including 43 triterpenoid saponins and 2 flavonoids which cont
ISSN:1001-5302
DOI:10.19540/j.cnki.cjcmm.20200623.204