Establishment and efficiency test of a clinical prediction model of bronchopulmonary dysplasia associated pulmonary hypertension in very premature infants

• Published in: Zhonghua er ke za zhi Vol. 62; no. 2; p. 129
• Main Authors: Cao, J K, Fan, H Q, Xiao, Y B, Wang, D, Liu, C G, Peng, X M, Gao, X R, Tang, S H, Han, T, Mei, Y B, Liang, H Y, Wang, S M, Wang, F, Li, Q P
• Format: Journal Article
• Language: Chinese
• Published: China 02.02.2024
• ISSN: 0578-1310
• DOI: 10.3760/cma.j.cn112140-20230912-00178

To develop a risk prediction model for identifying bronchopulmonary dysplasia (BPD) associated pulmonary hypertension (PH) in very premature infants. This was a retrospective cohort study. The clinical data of 626 very premature infants whose gestational age <32 weeks and who suffered from BPD were collected from October 1 , 2015 to December 31 , 2021 of the Seventh Medical Center of the People's Liberation Army General Hospital as a modeling set. The clinical data of 229 very premature infants with BPD of Hunan Children's Hospital from January 1 , 2020 to December 31 , 2021 were collected as a validation set for external verification. The very premature infants with BPD were divided into PH group and non PH group based on the echocardiogram after 36 weeks' corrected age in the modeling set and validation set, respectively. Univariate analysis was used to compare the basic clinical characteristics between groups, and collinearity exclusion was carried out between variables. The risk factors of BPD associated