Food protein-induced enterocolitis syndrome (FPIES) : a poorly known type of food allergy

Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy. Its pathophysiology is still poorly understood. FPIES mainly affects infant and young children, although cases have been reported in adults. Its symptomatology is restricted to gastrointestinal manifestations and...

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Bibliographic Details
Published inRevue médicale de Liège Vol. 76; no. 2; p. 77
Main Authors Pirotte, I, El Abd, K, Pekus, V, Colinet, S, Philippet, P
Format Journal Article
LanguageFrench
Published Belgium 01.02.2021
Subjects
Adult
Allergens
Animals
Cattle
Child
Child, Preschool
Dietary Proteins
Enterocolitis - diagnosis
Enterocolitis - etiology
Female
Food Hypersensitivity - diagnosis
Food Hypersensitivity - etiology
Humans
Infant
Syndrome
Food allergy
FPIES
mediated food allergy
IgE
induced enterocolitis syndrome
Cow’s milk allergy
Food protein
Non
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Summary:Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy. Its pathophysiology is still poorly understood. FPIES mainly affects infant and young children, although cases have been reported in adults. Its symptomatology is restricted to gastrointestinal manifestations and the onset of allergic reaction subsequent to exposure is delayed. The most common culprit for children is cow's milk. Initial clinical presentation of FPIES is oftentimes acute, though it can also be chronic. Diagnosis relies on clinical criteria, which have been recently redefined and subject to international consensus. Through two clinical cases, this report aims to describe the characteristics of this emerging disease as well as delineate the treatment thereof.
ISSN:0370-629X