Endoscopic treatment of chemical burns to the stomach with mucosa ulceration and necrosis

• Published in: Ėksperimental'nai͡a︡ i klinicheskai͡a︡ gastroėnterologii͡a no. 12; p. 62
• Main Authors: Nalbandova, D A, Sogreshilin, S S, Pinchuk, T P, Klokova, T V, Il'iashenko, K K
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2013
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Antioxidants - administration & dosage; Antioxidants - therapeutic use; Burns, Chemical - complications; Burns, Chemical - pathology; Burns, Chemical - therapy; Combined Modality Therapy; Gastroscopy - methods; Humans; Length of Stay; Low-Level Light Therapy - methods; Middle Aged; Necrosis; Picolines - administration & dosage; Picolines - therapeutic use; Stomach Ulcer - etiology; Stomach Ulcer - pathology; Stomach Ulcer - therapy; Time Factors; Treatment Outcome; Young Adult
• ISSN: 1682-8658

The prevalence of acute poisoning with caustic substances in Russia is higher than in other countries and is reported by different authors as accounting for 10-32% cases among the patients admitted to acute poisoning treatment centres. Especially unfavorable prognosis is considered for necrotizing burns to the stomach that increase the risk of severe complications leading to disability of patients. The study aimed at improving the treatment of necrotizing chemical burn to the stomach by the infusion of a 5% Mexidole solution into the edges of a burn lesion at different stages of the treatment course. The paper presents the outcomes of patients who sustained chemical burns to the stomach with mucosa ulceration and necrosis, and provides an assessment of early endoscopic treatment effect.