Concomitant impact of organic pathology on the development of cognitive impairment in patients with attack-like paranoid schizophrenia

The study included 47 patients (23 men, 24 women) with ICD-10 diagnosis of attack-like paranoid schizophrenia. Patients were divided into two groups: with- (25 patients) or without (22 patients) a concomitant organic disease. Memory, attention and thinking were assessed with psychometric tests. Inte...

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Published inZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Vol. 114; no. 5; p. 55
Main Authors Libin, L Ia, Tagil'tseva, A V, Lifanova, D E, Ganzenko, M A, Gritsevskaia, T M, Ivanov, M B
Format Journal Article
LanguageRussian
Published Russia (Federation) 2014
Subjects
Adult
Antipsychotic Agents - therapeutic use
Cognition Disorders - etiology
Cognition Disorders - prevention & control
Cognition Disorders - psychology
Female
Humans
Male
Middle Aged
Schizophrenia, Paranoid - complications
Schizophrenia, Paranoid - drug therapy
Schizophrenia, Paranoid - pathology
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Summary:The study included 47 patients (23 men, 24 women) with ICD-10 diagnosis of attack-like paranoid schizophrenia. Patients were divided into two groups: with- (25 patients) or without (22 patients) a concomitant organic disease. Memory, attention and thinking were assessed with psychometric tests. Inter- and intra-group differences were identified that indicated a considerable impact of a concomitant CNS organic pathology on the development of cognitive impairment in the schizophrenic process and active antipsychotic therapy. The data obtained can be used in the development of a differentiated approach to the treatment of patients with concomitant organic pathology.
ISSN:1997-7298