Sleep deprivation increases rat hypothalamic growth hormone-releasing hormone mRNA

Much evidence indicates that growth hormone-releasing hormone (GHRH) is involved in sleep regulation. We hypothesized that GHRH mRNA would increase and somatostatin (SRIH) mRNA would decrease during sleep deprivation.

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Bibliographic Details
Published inAmerican journal of physiology. Regulatory, integrative and comparative physiology Vol. 44; no. 6; pp. R1755 - R1761
Main Authors JIANYI ZHANG, ZUTANG CHEN, PING TAISHI, OBAL, F. JR, JIDONG FANG, KRUEGER, J. M
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.12.1998
Subjects
Anatomy & physiology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Hormones
Laboratory animals
Ribonucleic acid
RNA
Sleep
Sleep. Vigilance
Vertebrates: nervous system and sense organs
Deprivation
Rat
Somatotropin releasing factor
Rodentia
Central nervous system
Somatotropin hormone
Homeostasis
Hypothalamus
Diurnal variation
Gene expression
Endocrine secretion
Hypothalamic hormone
Vertebrata
Mammalia
Sleep
Hormone releasing factor
Brain (vertebrata)
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Summary:Much evidence indicates that growth hormone-releasing hormone (GHRH) is involved in sleep regulation. We hypothesized that GHRH mRNA would increase and somatostatin (SRIH) mRNA would decrease during sleep deprivation.
ISSN:0363-6119
1522-1490