Microbial biocenoss in chronic purulent otitis media

The objective of the present work was to study microflora in the middle ear of 100 patients aged from 30 to 70 years presenting with chronic purulent otitis media (CPOM) by microbiological and genetic (PCR) methods. An important role of persistence factors, pathogenicity, and microbial antibiotic re...

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Bibliographic Details
Published inVestnik otorinolaringologii no. 4; p. 17
Main Authors Beloglazova, N N, Vasil'eva, L I, Bragina, L E, Kiselev, V V, Naboka, Iu L
Format Journal Article
LanguageRussian
Published Russia (Federation) 2010
Subjects
Adult
Aged
Anti-Bacterial Agents - pharmacology
Bacteria - classification
Bacteria - drug effects
Bacteria - isolation & purification
Candida - classification
Candida - isolation & purification
Chronic Disease
Ear, Middle - microbiology
Ear, Middle - virology
Female
Humans
Male
Middle Aged
Otitis Media, Suppurative - microbiology
Otitis Media, Suppurative - virology
Viruses - classification
Viruses - isolation & purification
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Summary:The objective of the present work was to study microflora in the middle ear of 100 patients aged from 30 to 70 years presenting with chronic purulent otitis media (CPOM) by microbiological and genetic (PCR) methods. An important role of persistence factors, pathogenicity, and microbial antibiotic resistance in the development of CPOM was demonstrated. The frequency of occurrence of herpes and papilloma viruses was estimated. The most common form of the mixed infection was two-component virobacterial associations (46.2%). Three-component associations of viruses with bacteria (Chlamydiae or Mycoplasmas) formed less frequently (34.6%). In 19.2% of the cases, yeast-like fungi of the genus Candida were identified in these associations.
ISSN:0042-4668