Myocarditis and fibroplastic endocarditis in Wegener's granulomatosis

The paper describes an autopsy case of Wegener's granulomatosis with a rare variant of a cardiac lesion--the concurrence of aortic valvular disease (aortic regurgitation), fibroplastic endocarditis, and complete transverse blockade, followed by pacemaker implantation. The direct cause of death...

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Bibliographic Details
Published inArkhiv patologii Vol. 72; no. 1; p. 42
Main Authors Strizhakov, L A, Kogan, D N, Fedorov, D N, Krivosheev, O G, Semenkova, E N, Sorokin, Iu D
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.2010
Subjects
Adult
Aortic Valve Insufficiency - complications
Aortic Valve Insufficiency - pathology
Endocarditis - complications
Endocarditis - pathology
Fatal Outcome
Female
Granulomatosis with Polyangiitis - complications
Granulomatosis with Polyangiitis - pathology
Heart Failure - complications
Heart Failure - pathology
Humans
Multiple Organ Failure - complications
Multiple Organ Failure - pathology
Myocarditis - complications
Myocarditis - pathology
Respiratory Distress Syndrome, Adult - complications
Respiratory Distress Syndrome, Adult - pathology
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Summary:The paper describes an autopsy case of Wegener's granulomatosis with a rare variant of a cardiac lesion--the concurrence of aortic valvular disease (aortic regurgitation), fibroplastic endocarditis, and complete transverse blockade, followed by pacemaker implantation. The direct cause of death in the female patient was multiple organ dysfunction: progressive chronic heart failure, adult respiratory distress syndrome, acute hepatorenal failure, and pancreonecrosis. The data available in the Russian and foreign literature on investigations dealing with cardiac pathology in patients with Wegener's granulomatosis are analyzed.
ISSN:0004-1955