Calmodulin levels are dynamically regulated in living vascular smooth muscle cells

The total unbound calmodulin (i.e., not bound to target proteins) level in living smooth muscle cells from the ferret portal vein was monitored with a low-affinity, calmodulin-binding peptide tagged with an environmentally sensitive fluorophore.

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Bibliographic Details
Published inAmerican journal of physiology. Heart and circulatory physiology Vol. 49; no. 3; pp. H1422 - H1426
Main Authors HULVERSHORN, Justin, GALLANT, Cynthia, WANG, C.-L. Albert, DESSY, Chantal, MORGAN, Kathleen G
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.03.2001
Subjects
Biological and medical sciences
Blood vessels
Blood vessels and receptors
Calcium
Cells
Fluorescence
Fundamental and applied biological sciences. Psychology
Medical research
Peptides
Vertebrates: cardiovascular system
Fissipedia
Carnivora
Smooth muscle
Biological activity
Binding protein
Vertebrata
Regulation(control)
Mammalia
Calcium ion
Actin
Blood vessel
Animal
Ferret
Circulatory system
Intracellular
Portal vein
Calmodulin
Quantitative analysis
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Summary:The total unbound calmodulin (i.e., not bound to target proteins) level in living smooth muscle cells from the ferret portal vein was monitored with a low-affinity, calmodulin-binding peptide tagged with an environmentally sensitive fluorophore.
ISSN:0363-6135
1522-1539