Uptake1 inibition in reperfusion: noradrenalin dynamic and myocardiola infraction size

• Published in: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Vol. 96; no. 2; p. 101
• Main Authors: Naumenko, S E, Latysheva, T V, Gilinskiĭ, M A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.02.2010
• Subjects: Animals; Desipramine - pharmacology; Enzyme Inhibitors - pharmacology; Male; Myocardial Infarction - metabolism; Myocardial Infarction - pathology; Myocardium - metabolism; Myocardium - pathology; Norepinephrine - metabolism; Rats; Reperfusion

To determine the effect of uptake 1 inhibition in reperfusion after myocardial ischcmia upon noradrenalin dynamic and myocardial infarction size, 14 male Wistar rats anesthetized with urethane were randomly divided into 2 groups and subjected to 30 min coronary occlusion and subsequent 120 min reper...