Childhood cutaneous granular cell tumor: case report

• Published in: Archivos argentinos de pediatría Vol. 110; no. 2; pp. e17 - e20
• Main Authors: Di Martino Ortiz, Beatriz, Contreras, Romina, Rodríguez Oviedo, Lourdes, Argüello, Gladys, Rodríguez, Mirtha, Knopfelmacher, Oilda, Bolla, Lourdes
• Format: Journal Article
• Language: Spanish
• Published: Argentina 01.04.2012
• Subjects: Child; Granular Cell Tumor - pathology; Humans; Male; Skin Neoplasms - pathology
• ISSN: 1668-3501
• DOI: 10.1590/S0325-00752012000200014

Granular cell tumors (GCT) are benign neoplasms of distinctive differentiation when observed by light microscopy, which are characterized by the presence of cells with abundant granular eosinophilic cytoplasm. Reports in children are extremely rare. An 11-year-old male patient presented with a nodule after six months of evolution, which progressively increased in size, asymptomatic, localized on the back. Exploration revealed an oval nodule, 1.5 cm in diameter, movile, nonadherent, and painless. Histological study revealed a non-encapsulated tumorous lesion formed by large cells, organized in clusters, of abundant cytoplasm containing eosinophilic granules and small, centrally located nuclei. Immunohistochemical study demonstrated the presence of S100. Treatment indicated was local conservative surgical excision. We emphasize the need to biopsy persistent ulcerated solitary nodules, for diagnostic accuracy, highlighting the importance of histopathology because clinical diagnosis is difficult and almost never we think about it, unless the tumor arises on the tongue.