Detection of circulation of West Nile virus in equine in the north-west of Tunisia

Two outbreaks of West Nile Fever (FWN) were observed in the Sahel of Tunisia in 1997 and 2003. Several cases of meningitis and meningoencephalitis have been described in humans during these two outbreaks. However, no animal or clinical findings or seroconversion have been detected despite a high ser...

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Published inBulletin de la Societe de pathologie exotique (1990) Vol. 104; no. 4; pp. 266 - 271
Main Authors Ben Hassine, T, Hammami, S, Elghoul, H, Ghram, A
Format Journal Article
LanguageFrench
Published France 01.10.2011
Subjects
Analysis of Variance
Animals
Antibodies, Viral - blood
Cattle
Disease Outbreaks
Enzyme-Linked Immunosorbent Assay
Horses - virology
Humans
Immunoglobulin G - blood
Seroepidemiologic Studies
Tunisia - epidemiology
West Nile Fever - epidemiology
West Nile virus - immunology
Tunisia
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Summary:Two outbreaks of West Nile Fever (FWN) were observed in the Sahel of Tunisia in 1997 and 2003. Several cases of meningitis and meningoencephalitis have been described in humans during these two outbreaks. However, no animal or clinical findings or seroconversion have been detected despite a high seroprevalence in human beings found around the affected areas. Few data are available regarding the spreading of this virus in other parts of the country. The purpose of this study was to detect a possible WNV spread in horses in some areas of Tunisia considered to be at risk for WNV but which had not been affected by previous outbreaks. A total of 133 equine blood samples were collected in six delegations from three governorates in the north-west of Tunisia. A second blood sampling was taken from animals that were tested negative after the first sampling for IgG to identify possible seroconversion. Detection of IgG was done using competitive ELISA. A significant viral spread was detected in the study area. Out of 133 samples tested for IgG during the first sampling, 36 samples were tested positive (27.1%). Two seroconversions were detected between September and October 2008 out of 84 samples tested. Statistical analysis showed a significant association between the presence of a wetland within 10 km and seroconversion. The presence of cattle seems to be a protective factor.
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ISSN:0037-9085
DOI:10.1007/s13149-011-0173-1