Conditioned suppression of contact sensitivity is independent of sympathetic splenic innervation

Exton et al investigated the role of sympathetic innervation of the spleen in conditioned suppression of a contact hypersensitivity (CHS) reaction. The data indicate that behavioral conditioning using CsA produces alternations of CHS that, unlike conditioned prolongation of heart allograft survival,...

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Bibliographic Details
Published inAmerican journal of physiology. Regulatory, integrative and comparative physiology Vol. 48; no. 4; pp. R1310 - R1315
Main Authors EXTON, Michael S, ELFERS, Alexandra, JEONG, Woo-Young, BULL, Diane F, WESTERMANN, Jürgen, SCHEDLOWSKI, Manfred
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.10.2000
Subjects
Behavioral psychophysiology
Behavioral sciences
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Miscellaneous
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Spleen
Spleen
Immune response
Rat
Hypersensitivity
Suppression
Rodentia
Sympathetic nervous system
Classical conditioning
Vertebrata
Sensitivity
Mammalia
Autonomic nervous system
Animal
Ciclosporin
Sensitization
Chemical stimulus
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Summary:Exton et al investigated the role of sympathetic innervation of the spleen in conditioned suppression of a contact hypersensitivity (CHS) reaction. The data indicate that behavioral conditioning using CsA produces alternations of CHS that, unlike conditioned prolongation of heart allograft survival, are independent of sympathetically regulated conditioned alterations in the spleen.
ISSN:0363-6119
1522-1490