CD14++CD16- and CD14+CD16+ human monocytes adhesion to endothelial cells

• Published in: T͡S︡itologii͡a Vol. 52; no. 5; p. 380
• Main Authors: Starikova, E A, Lebedeva, A M, Freĭdlin, I S
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2010
• Subjects: Cell Adhesion - drug effects; Cells, Cultured; Endothelial Cells - physiology; Humans; Interleukin-4 - pharmacology; Lipopolysaccharide Receptors - immunology; Monocytes - drug effects; Monocytes - immunology; Monocytes - physiology; Receptors, IgG - immunology; Tumor Necrosis Factor-alpha - pharmacology

Two subsets of monocytes were identified in humans and other mammals blood based on different levels of CD14 and CD16 expression. These subsets have different patterns of adhesion molecules and chemokine receptors, which suggest different modes of interaction with endothelium and tissue traffic. Her...