Efficacy and tolerance of a calcium-magnesium-aspartate solution in the treatment of hypocalcemic parturient paresis in cows

• Published in: Berliner und Münchener tierärztliche Wochenschrift Vol. 112; no. 10-11; p. 400
• Main Authors: Andresen, U, Kietzmann, M, Andresen, P
• Format: Journal Article
• Language: German
• Published: Germany 01.10.1999
• Subjects: Animals; Aspartic Acid - administration & dosage; Aspartic Acid - therapeutic use; Calcium Compounds - administration & dosage; Calcium Compounds - blood; Calcium Compounds - therapeutic use; Cattle; Cattle Diseases - drug therapy; Female; Hypocalcemia - drug therapy; Hypocalcemia - etiology; Hypocalcemia - veterinary; Magnesium Compounds - administration & dosage; Magnesium Compounds - blood; Magnesium Compounds - therapeutic use; Parturient Paresis - complications; Parturient Paresis - drug therapy; Pregnancy; Solutions
• ISSN: 0005-9366

The systemic tolerance of a solution of calcium aspartate and magnesium aspartate was studied in 7 cows. Intravenously administered dosages of 500 ml per cow were well tolerated. A twofold increase of the serum calcium concentration was measured. In 2 cows which were treated with 1000 ml of the solution a threefold increased calcium concentration and heart arrhythmia were found. The clinical efficacy of the solution was demonstrated in a study with 44 hypocalcemic cows. A long lasting increase of the serum calcium as well as an enhanced phosphorus concentration were measurable. In conclusion, the calcium-magnesium-aspartate solution seems to be an efficacious and well tolerated alternative for the treatment of hypocalcemia in cows.