Gene therapy in liver diseases

The basic principles of gene therapy, ex vivo and in vivo gene transfers and various vectors have been reviewed first in the paper. Then the models for clinical application are shown, including the recent results of experimental studies, with special regard to the treatment of liver diseases and amo...

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Bibliographic Details
Published inOrvosi hetilap Vol. 143; no. 3; p. 125
Main Authors Pár, Alajos, Lakatos, Péter László, Abonyi, Margit, Szalay, Ferenc, Nagy, Zsuzsanna, Mózsik, Gyula
Format Journal Article
LanguageHungarian
Published Hungary 20.01.2002
Subjects
Animals
Carcinoma, Hepatocellular - genetics
Carcinoma, Hepatocellular - therapy
Gene Transfer Techniques
Genetic Therapy - methods
Humans
Liver Diseases - genetics
Liver Diseases - therapy
Liver Neoplasms - genetics
Liver Neoplasms - therapy
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Summary:The basic principles of gene therapy, ex vivo and in vivo gene transfers and various vectors have been reviewed first in the paper. Then the models for clinical application are shown, including the recent results of experimental studies, with special regard to the treatment of liver diseases and amongst them hepatocellular carcinoma. Gene therapy is still in preclinical stage. Due to the ongoing intensive genetic studies and if the existing problems being resolved in this field, we can predict that the early years of this millennium gene therapy will be a useful modality in the clinical hepatology as well.
ISSN:0030-6002