Beta-2 microglobulinuria in children with vesico-ureteral reflux and recurrent urinary tract infections

Recurrent urinary tract infections in children with vesico-ureteral reflux are the one of risk factors in the process of reflux nephropathy. One of markers of early kidney parenchyma damage is beta 2-microglobulin. The aim of the study was to evaluate the value of beta 2-microglobulin excretion in u...

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Bibliographic Details
Published inPolski merkuriusz lekarski Vol. 8; no. 46; p. 240
Main Authors Kamińska, A, Jung, A, Olszewski, S, Muszyńska, J, Dadas, E
Format Journal Article
LanguagePolish
Published Poland 01.04.2000
Subjects
Adolescent
beta 2-Microglobulin - blood
beta 2-Microglobulin - urine
Child
Child, Preschool
Female
Humans
Infant
Male
Recurrence
Urinary Tract Infections - blood
Urinary Tract Infections - complications
Vesico-Ureteral Reflux - blood
Vesico-Ureteral Reflux - complications
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Summary:Recurrent urinary tract infections in children with vesico-ureteral reflux are the one of risk factors in the process of reflux nephropathy. One of markers of early kidney parenchyma damage is beta 2-microglobulin. The aim of the study was to evaluate the value of beta 2-microglobulin excretion in urine and its serum levels in children with vesico-ureteral reflux and recurrent urinary tract infections. It was found that abnormal urinary excretion of beta 2-microglobulin and its serum levels of proceeded post-inflammatory changes in kidney parenchyma observed in imaging examinations of urinary tract and impared parameters of renal function in biochemical analyses.
ISSN:1426-9686