Sex influences on opioid pharmacotherapy
Opioids make up a pharmacological group employed from antiquity for the treatment of various ailments. Nowadays they are far used like palliative of acute or chronic pains of high intensity considering their great analgesic effectiveness. During the last years, many articles have reported sex-relate...
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Published in | Vertex (Buenos Aires, Argentina) Vol. 18; no. 76; p. 413 |
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Main Author | |
Format | Journal Article |
Language | Spanish |
Published |
Argentina
01.11.2007
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Subjects | |
Online Access | Get more information |
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Summary: | Opioids make up a pharmacological group employed from antiquity for the treatment of various ailments. Nowadays they are far used like palliative of acute or chronic pains of high intensity considering their great analgesic effectiveness. During the last years, many articles have reported sex-related differences in the response of laboratory animals to several opioids. These data is according to the knowledge about sex determining both brain structure and functions. In addition, this sexual dimorphism has been recently reported for women and men treated with opioids. The relevance of this information could give rise to a revision of the dosage traditionally employed by physicians in either sex. The present article covers the main aspects of this subject considering its significance in the pharmacotherapy with opioids. |
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ISSN: | 0327-6139 |