Carcinogenic effects of low radiation doses

The carcinogenic effect of low doses of ionizing radiation has been a matter of much debate over the last few years. The French Academy of Science published a report on the subject in 1995. The central point of discussion concerns the validity of the linear no threshold relationship for estimating,...

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Bibliographic Details
Published inCancer radiothérapie Vol. 3; no. 3; p. 203
Main Author Tubiana, M
Format Journal Article
LanguageFrench
Published France 01.05.1999
Subjects
DNA - radiation effects
Dose-Response Relationship, Radiation
Humans
Japan
Leukemia, Radiation-Induced - etiology
Linear Models
Mutation
Neoplasms, Radiation-Induced - etiology
Occupational Exposure - adverse effects
Radiation Dosage
Radioactive Fallout
Radioisotopes - adverse effects
Relative Biological Effectiveness
Japan
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Summary:The carcinogenic effect of low doses of ionizing radiation has been a matter of much debate over the last few years. The French Academy of Science published a report on the subject in 1995. The central point of discussion concerns the validity of the linear no threshold relationship for estimating, by extrapolation, the carcinogenic effect of low doses. The aim of this article is to analyze the epidemiological data on the effect of low doses and the biological data on the mechanisms of carcinogenesis that have been obtained since 1995. These data strengthen doubts concerning the validity of current risk evaluations at low doses.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:1278-3218
DOI:10.1016/s1278-3218(99)80053-5