Effects of perstarium on the systolic and diastolic functions of the myocardium in patients with chronic cardiac failure

The aim of the study was to assess prestarium effects on systolic and diastolic cardiac functions in 38 patients with ischemic heart disease and chronic cardiac failure (NYHA functional class II-IV) by biventricular balanced radioventriculography. Both left and right ventricular diastolic dysfunctio...

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Bibliographic Details
Published inKlinicheskaia meditsina Vol. 79; no. 8; p. 20
Main Authors Fomina, I G, Georgadze, Z O, Sinitsyna, M G, Gaĭdamakina, N E, Nagieva, A Z, Matveev, V V
Format Journal Article
LanguageRussian
Published Russia (Federation) 2001
Subjects
Adult
Aged
Angiotensin-Converting Enzyme Inhibitors - administration & dosage
Angiotensin-Converting Enzyme Inhibitors - pharmacology
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Blood Pressure - drug effects
Chronic Disease
Female
Heart Failure - drug therapy
Heart Failure - physiopathology
Humans
Hypertension - drug therapy
Male
Middle Aged
Perindopril - administration & dosage
Perindopril - pharmacology
Perindopril - therapeutic use
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Summary:The aim of the study was to assess prestarium effects on systolic and diastolic cardiac functions in 38 patients with ischemic heart disease and chronic cardiac failure (NYHA functional class II-IV) by biventricular balanced radioventriculography. Both left and right ventricular diastolic dysfunction was found. A course of prestarium treatment caused different alterations in ventricular contractility. 64.2% patients of those who had right ventricular ejection fraction < 40% achieved an increase in right and left ventricular ejection fraction. Improved diastolic function of the myocardium was registered in 71% patients.
ISSN:0023-2149