Mast cells and innervation of the wall of the hyperactive urinary bladder

Anterior urinary bladder wall biopsy specimens were examined in 24 males and 4 females, aged 52 to 76 years, who had been suffering from the hyperactive urinary bladder for 1-10 years. Increases in the number and activity of interstitial mast cells and their degranulation and the symptoms of chronic...

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Bibliographic Details
Published inArkhiv patologii Vol. 69; no. 6; p. 29
Main Authors Loran, O B, Shvalev, V N, Pisarev, S A, Kleĭmenova, N V, Sukhorukov, V S
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.2007
Subjects
Aged
Female
Humans
Male
Mast Cells - physiology
Mast Cells - ultrastructure
Middle Aged
Urinary Bladder - innervation
Urinary Bladder - pathology
Urinary Bladder, Overactive - pathology
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Summary:Anterior urinary bladder wall biopsy specimens were examined in 24 males and 4 females, aged 52 to 76 years, who had been suffering from the hyperactive urinary bladder for 1-10 years. Increases in the number and activity of interstitial mast cells and their degranulation and the symptoms of chronic immune inflammation were revealed. Neuromuscular spastic dysfunction of the detrusor is considered to result from the activation of mast cells.
ISSN:0004-1955