Potential to predict the risk of developing proliferative vitreoretinopathy with the analysis of clinical factors of regmatogenous retinal detachments

• Published in: Archivos de la Sociedad Española de Oftalmología Vol. 75; no. 12; pp. 807 - 812
• Main Authors: Rodríguez de la Rúz Franch, E, Aragón Roca, J A, Pastor Jimeno, J C, Carrasco Herrero, B, González Rodríguez, J C, Alvarez Requejo, A, Martín De Diego, I, Giraldo Arguello, A
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.12.2000
• Subjects: Female; Humans; Male; Middle Aged; Prognosis; Retinal Detachment - complications; Retrospective Studies; Risk Factors; Vitreoretinopathy, Proliferative - diagnosis; Vitreoretinopathy, Proliferative - epidemiology; Vitreoretinopathy, Proliferative - etiology
• ISSN: 0365-6691; 1989-7286

To investigate the possibility of classifying RD patients in different risk groups according to their probability of developing PVR. This retrospective study included 298 RD patients who underwent RD surgery, with either no PVR or with PVR grade B or less. Risk factors were evaluated by single and multiple logistic regression analysis to obtain risk factors of PVR. According to the results of the regression analysis, a score was applied to the different risk factors. The sum of these scores provided a final score for each patient, which was used to divide patients in three groups according to their risk of developing PVR. By multiple logistic regression analysis, the following risk factors for developing PVR were identified: Preoperative PVR grade A or B, RD involving 4 quadrants, previous intraocular surgery, endolaser application, and intraocular gas injection. Three protective factors were also identified: RD in the fellow eye, postoperative ocular hypertension, and total reattachment 24 hours after surgery. Patients were divided in three groups according to their probability to develop PVR: Low risk (192 patients, 11.5% developed PVR), moderate risk (70 patients, 50.0% developed PVR) and high risk (36 patients, 80.6% developed PVR). It is possible to ascribe patients to a low, moderate or high risk probability of developing PVR and these data could be useful to establish a prophylactic treatment for PVR. A larger and prospective study is needed to corroborate these data and to obtain new indicators.