Effects of lipids obtained from the liver of marine animals on the immunologic status and hematologic indices of rats

• Published in: Voprosy pitaniia Vol. 69; no. 1-2; p. 10
• Main Authors: Mustafina, O K, Trushina, E N, Sergeeva, K V, Aseeva, L E, Levachev, M M
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2000
• Subjects: Animals; Blood Cells - drug effects; Dietary Fats - pharmacology; Fatty Acids, Omega-3 - pharmacology; Helianthus; Hemoglobins - drug effects; Immunity - drug effects; Male; Plant Oils - pharmacology; Rats; Rats, Wistar
• ISSN: 0042-8833

The influence of lipids received from liver of king crab (Paralithodes camtschatica) and liver of pollack on some indices of immunologic status of an organism and hematologic indices in rats was studied. The animals were divided into three groups in dependence from kind of lipid in diet: the control group received in the composition of lipid component of diet--lard and sunflower oil in the ratio 1:1, the second group--lard and lipid from pollack liver (1:1), the third group--lard and lipid from crabs liver (1:1). The differences of rations concerned their lipid component. The content of triglycerides in a liver of pollack compounded--73%, in a liver of crabs--50%, the content of phospholipids in a liver of pollack--12%, in a liver of crabs it is much more--20%; the total sun of omega-3 acids in the experimental group is practically identical: 23.8 and 23.1% accordingly. Some simulate influence of lipid from liver of crabs on the quantity of antibody forming cells of a spleen was noted. The tendency to decreasing of indices of humoral immunity was founded in rats, which received diet with lipid from liver of pollack. The decrease of the quantity of lymphocytes and the increase of the quantity of eosinophilic leukocytes in a peripheral blood of animals this group was noted in comparison with control and other experimental groups.