Research on active constituents research of gualou xiebai baijiutang (III). The active flavanoids

To observe the substance basis of actions of Gualou xiebai baijiutang. Guided by bioactivities, the prescription was isolated and purified by chemical and chromatographic methods, and the structures were identified by chemical and spectral methods. 4 compounds were isolated from active parts. 3 comp...

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Bibliographic Details
Published inZhongguo zhongyao zazhi Vol. 28; no. 5; p. 420
Main Authors He, Xiang-jiu, Wang, Nai-li, Qiu, Feng, Yao, Xin-sheng
Format Journal Article
LanguageChinese
Published China 01.05.2003
Subjects
Allium - chemistry
Animals
Disaccharides - chemistry
Disaccharides - isolation & purification
Disaccharides - pharmacology
Drug Combinations
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - isolation & purification
Drugs, Chinese Herbal - pharmacology
Ethanol
Flavonoids - chemistry
Flavonoids - isolation & purification
Flavonoids - pharmacology
Plants, Medicinal - chemistry
Platelet Aggregation - drug effects
Quercetin - isolation & purification
Rats
Trichosanthes - chemistry
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Summary:To observe the substance basis of actions of Gualou xiebai baijiutang. Guided by bioactivities, the prescription was isolated and purified by chemical and chromatographic methods, and the structures were identified by chemical and spectral methods. 4 compounds were isolated from active parts. 3 compounds were isolated for the first time from Trichosanthes kirilowii and Allium macrostemon. Compound 1 had a good activity against platelet aggregation.
ISSN:1001-5302