The study of the human complement cascade of proteolysis as a target of laser irradiation
Samples of human blood plasma were irradiated with the laser beam (lamda=633 nm, P=13 mW, t=20 min) in vitro. In experimental and control (incubated in the dark) samples the complement hemolytic activity was measured. Laser irradiation had minor influence on the duration of lag-period and the rate o...
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Published in | Biomeditsinskaia khimiia Vol. 55; no. 1; p. 68 |
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Main Authors | , , , , |
Format | Journal Article |
Language | Russian |
Published |
Russia (Federation)
01.01.2009
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Subjects | |
Online Access | Get more information |
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Summary: | Samples of human blood plasma were irradiated with the laser beam (lamda=633 nm, P=13 mW, t=20 min) in vitro. In experimental and control (incubated in the dark) samples the complement hemolytic activity was measured. Laser irradiation had minor influence on the duration of lag-period and the rate of complement-dependent hemolysis via classical and alternative pathways; it also did not alter the functional activity of factor B, components C2 and C3. Nevertheless laser irradiation effect was seen in essential reduction of a bystander lysis coefficient. This new fact can elucidate some aspects of the clinical effectiveness of the blood laser irradiation. |
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ISSN: | 2310-6972 |