Clostridium infections in leukemias and malignant neoplasms

This review describes the subject of clostridial complications in leukemia and malignant neoplasms. These complications include bacteremia and spontaneous nontraumatic gas gangrene of the muscles. The mechanism of anaerobic microenvironment formation, which is necessary for infection development in...

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Bibliographic Details
Published inPolski merkuriusz lekarski Vol. 17; no. 100; p. 403
Main Authors Wallner, Grzegorz, Misiuna, Paweł, Cygan, Wiesław, Cygan, Zygmunt
Format Journal Article
LanguagePolish
Published Poland 01.10.2004
Subjects
Anti-Bacterial Agents - therapeutic use
Clostridium Infections - etiology
Clostridium Infections - microbiology
Clostridium Infections - physiopathology
Clostridium perfringens
Gas Gangrene - etiology
Humans
Leukemia - complications
Leukemia - physiopathology
Neoplasms - complications
Neoplasms - physiopathology
Risk Factors
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Summary:This review describes the subject of clostridial complications in leukemia and malignant neoplasms. These complications include bacteremia and spontaneous nontraumatic gas gangrene of the muscles. The mechanism of anaerobic microenvironment formation, which is necessary for infection development in neoplastic tumors, is also demonstrated. The role of risk factors contributing to the occurrence of clostridial infections is discussed. Further, the etiology of infections, related mostly to the action of Clostridium septicum and Clostridium perfringens toxins, as well as the pathogenesis of complications and their clinical course are indicated. Present treatment strategies are also briefly described.
ISSN:1426-9686