A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences

It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, com...

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Published inMolekuliarnaia biologiia Vol. 35; no. 6; p. 1015
Main Authors Gusev, V D, Nemytikova, L A, Chuzhanova, N A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.2001
Subjects
Databases, Nucleic Acid
Evolution, Molecular
Repetitive Sequences, Nucleic Acid
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Abstract It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5'-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example.
AbstractList It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5'-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example.
Author Nemytikova, L A
Chuzhanova, N A
Gusev, V D
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Snippet It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The...
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SubjectTerms Databases, Nucleic Acid
Evolution, Molecular
Repetitive Sequences, Nucleic Acid
Title A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences
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Volume 35
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