A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences
It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, com...
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Published in | Molekuliarnaia biologiia Vol. 35; no. 6; p. 1015 |
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Main Authors | , , |
Format | Journal Article |
Language | Russian |
Published |
Russia (Federation)
01.11.2001
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Subjects | |
Online Access | Get more information |
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Summary: | It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5'-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example. |
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ISSN: | 0026-8984 |