A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences

It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, com...

Full description

Saved in:
Bibliographic Details
Published inMolekuliarnaia biologiia Vol. 35; no. 6; p. 1015
Main Authors Gusev, V D, Nemytikova, L A, Chuzhanova, N A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.2001
Subjects
Databases, Nucleic Acid
Evolution, Molecular
Repetitive Sequences, Nucleic Acid
Online AccessGet more information

Cover

More Information
Summary:It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5'-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example.
ISSN:0026-8984