Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps

To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps. Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age. Therapeutic dose of Solco...

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Bibliographic Details
Published inŽurnal mikrobiologii, ėpidemiologii i immunobiologii no. 4; p. 53
Main Authors Dolgushin, I I, Andreeva, Iu S, Ryzhkova, A I, Savochkina, A Iu, Mezentseva, E A, Nikushkina, K V, Abramovskikh, O S, Marachev, S I, Matveeva, D N
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.2009
Subjects
Adult
Bacterial Vaccines - administration & dosage
Bacterial Vaccines - immunology
Dose-Response Relationship, Immunologic
Female
Humans
Immunity, Innate
Mucous Membrane - immunology
Neutrophils - immunology
Neutrophils - ultrastructure
Vagina - immunology
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Summary:To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps. Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age. Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps. Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.
ISSN:0372-9311