Experience with using of solutions of hydroxyethyl starch (refortan and voluven) in neuroanesthesiology

The investigation has shown that solutions of hydroxyethyl starch included in complex infusion therapy facilitate stabilization of hemodynamics in neurosurgical patients during surgery. Refortan exerts a more pronounced effect on the indices of hemodynamics as compared with voluven, but its modifyin...

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Bibliographic Details
Published inVestnik hirurgii im. I.I. Grekova Vol. 166; no. 6; p. 56
Main Authors Kondrat'ev, A N, Savvina, I A, Novikov, V Iu, Driagina, N V
Format Journal Article
LanguageRussian
Published Russia (Federation) 2007
Subjects
Anesthesia - methods
Hemodynamics - drug effects
Homeostasis - drug effects
Humans
Hydroxyethyl Starch Derivatives - administration & dosage
Infusions, Intravenous
Intraoperative Care - methods
Middle Aged
Nervous System Diseases - physiopathology
Nervous System Diseases - surgery
Neurosurgical Procedures - methods
Phenoxyacetates - administration & dosage
Plasma Substitutes - administration & dosage
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Summary:The investigation has shown that solutions of hydroxyethyl starch included in complex infusion therapy facilitate stabilization of hemodynamics in neurosurgical patients during surgery. Refortan exerts a more pronounced effect on the indices of hemodynamics as compared with voluven, but its modifying action on the hemostasis system is also more pronounced. These medicines used in doses 6-8 ml/kg fail to have substantial effects on efficiency of hemostasis in the brain wound and do not increase risk of postoperative hemorrhagic complications.
ISSN:0042-4625