The regulation of vitamin D metabolism and PTH secretion by phosphorus
Vitamin D and PTH are major hormones that regulate calcium metabolism. Also, the serum level of phosphorus is known to change according to the level of calcium and to regulate the vitamin D and PTH. Recently, cloning of 1alpha- hydroxylase cDNA which is the key enzyme in vitamin D metabolism, enable...
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| Published in | Clinical calcium Vol. 11; no. 10; p. 1302 |
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| Main Authors | , |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japan
01.10.2001
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| Online Access | Get more information |
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| Summary: | Vitamin D and PTH are major hormones that regulate calcium metabolism. Also, the serum level of phosphorus is known to change according to the level of calcium and to regulate the vitamin D and PTH. Recently, cloning of 1alpha- hydroxylase cDNA which is the key enzyme in vitamin D metabolism, enabled us to examine the effects of phosphorus in vitamin D metabolism at a molecular level. Furthermore, the direct effect of phosphorus in PTH synthesis is being elucidated in recent reports. In this paper, we summarized the regulation of vitamin D and PTH by phosphorus. |
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| ISSN: | 0917-5857 |