Collective poliomyelitis immunity in the adult population and its impact on eradication of this infection

Collective poliomyelitis immunity was studied in 6339 donors from 19 towns and cities of Russia. Its stress substantially varied in different towns and cities. Studies of strain-specific antibodies to vaccine and wild viruses of poliomyelitis in donors from 4 towns established that the immune person...

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Bibliographic Details
Published inVoprosy virusologiĭ Vol. 52; no. 3; p. 44
Main Authors Seĭbil', V B, Malyshkina, L P, Lavrova, I K, Efimova, V F
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.05.2007
Subjects
Adolescent
Adult
Aged
Antibodies, Viral - blood
Antibodies, Viral - immunology
Antibody Specificity
Female
Humans
Immunization Programs
Male
Middle Aged
Poliomyelitis - blood
Poliomyelitis - etiology
Poliomyelitis - prevention & control
Poliovirus - immunology
Poliovirus Vaccine, Oral - administration & dosage
Poliovirus Vaccine, Oral - immunology
Poliovirus Vaccines - adverse effects
Poliovirus Vaccines - immunology
Risk Factors
Russia - epidemiology
Seroepidemiologic Studies
Tissue Donors
Urban Population
Vaccination - adverse effects
Vaccination - methods
Russia
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Summary:Collective poliomyelitis immunity was studied in 6339 donors from 19 towns and cities of Russia. Its stress substantially varied in different towns and cities. Studies of strain-specific antibodies to vaccine and wild viruses of poliomyelitis in donors from 4 towns established that the immune persons were more in the town where wild polioviruses had previously circulated than in those where the circulation of wild polioviruses had been limited and immunity resulted from vaccination. Circulation of vaccine viruses and reversion of their neurovirulent properties should be expected in the town where there are low collective poliomyelitis immunity rates. It is concluded that it is impossible to eradicate poliomyelitis as infection today; it is possible only to eliminate the disease if further vaccination of children is performed with live poliomyelitis vaccine.
ISSN:0507-4088