Glycophorin in forensic medicine

Immunohistological evidence of glycophorin from paraffin sections of tissues fixed with formol, makes its possible to visualize membranes of preserved erythrocytes and fragments after their disintegration. This fact permits even after development of post-mortem changes to differentiate actual extrav...

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Bibliographic Details
Published inSoudni lekarstvi Vol. 45; no. 2; p. 22
Main Authors Klír, P, Toupalík, P, Bouska, I, Jezková, J
Format Journal Article
LanguageCzech
Published Czech Republic 01.05.2000
Subjects
Erythrocyte Membrane - chemistry
Forensic Medicine
Glycophorin - analysis
Hematoma - metabolism
Humans
Immunohistochemistry
Postmortem Changes
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Summary:Immunohistological evidence of glycophorin from paraffin sections of tissues fixed with formol, makes its possible to visualize membranes of preserved erythrocytes and fragments after their disintegration. This fact permits even after development of post-mortem changes to differentiate actual extravasation, manifested by a positive finding of glycophorin from mere infiltration of tissue by blood pigment after death, where glycophorin is lacking. The method is very sensitive and can reveal even very discrete haemorrhage. From different grades of erythrocyte disintegration in haematomas in the same subject sometimes conclusions can be drawn also on the different time of development of traumatic tissue changes.
ISSN:0371-1854