Effects of 21 d -6 degrees head down bed-rest on pulmonary gas distribution and little airway function

To probe the effect of 21 d -6 degrees head down bed-rest (HDBR) on pulmonary gas distribution and little airway function. The indices of the pulmonary gas distribution and little airway function (delta N2, CV, CV/VC%, LCI) were measured in 16 healthy male subjects before, during and after 21 d -6 d...

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Published inHang tian yi xue yu yi xue gong cheng Vol. 16; no. 2; p. 93
Main Authors Wei, Shi-qiang, Su, Shuang-ning, Lu, Li-Li, Li, Yong-zhi, Zhong, Chong-fa, Ren, Hong-ru
Format Journal Article
LanguageChinese
Published China 01.04.2003
Subjects
Adolescent
Adult
Bed Rest
Head-Down Tilt
Humans
Lung - metabolism
Lung - physiology
Male
Nitrogen - metabolism
Pulmonary Gas Exchange - physiology
Pulmonary Ventilation - physiology
Respiratory Function Tests
Respiratory Physiological Phenomena
Supine Position
Weightlessness Simulation
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Summary:To probe the effect of 21 d -6 degrees head down bed-rest (HDBR) on pulmonary gas distribution and little airway function. The indices of the pulmonary gas distribution and little airway function (delta N2, CV, CV/VC%, LCI) were measured in 16 healthy male subjects before, during and after 21 d -6 degrees HD-BR. Comparing with before and early days of HDBR, recovery supine delta N2 increased significantly. CV increased significantly only on the first day of HDBR, and changes of CV/VC% were same as CV. The changes of LCI were not significant. The indices of pulmonary gas distribution were affected by 21 d -6 degrees HDBR. Pulmonary gas distribution was more uneven during and after 21 d -6 degrees HDBR.
ISSN:1002-0837