Photodynamic therapy for choroidal neovascularization not caused by age related macular degeneration or pathologic myopia

• Published in: Archivos de la Sociedad Española de Oftalmología Vol. 78; no. 9; pp. 471 - 476
• Main Authors: Torrón Fernández-Blanco, C, Pérez Oliván, S, Ferrer Novella, E, Ruiz-Moreno, O, Marcuello Melendo, B, Honrubia López, F M
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.09.2003
• Subjects: Aged; Choroidal Neovascularization - drug therapy; Female; Humans; Macular Degeneration; Male; Middle Aged; Myopia; Photochemotherapy; Retrospective Studies
• ISSN: 0365-6691

To assess the effects of photodynamic therapy (PDT) with verteporfin on visual acuity (VA) and fluorescein angiography, in patients with subfoveal choroidal neovascularization (CNV) not secondary to age related macular degeneration (AMD) or pathologic myopia. 113 eyes from 104 patients underwent PDT due to subfoveal CNV from July 2001 to June 2002. In this study only those patients with CNV not related to AMD or pathologic myopia were included. Fluorescein angiography and visual acuity were evaluated. 9 eyes from 8 patients (8.03%) showed distinct causes of CNV: 3 were idiopathic cases, 1 suffered angioid streaks, 1 was secondary to laser photocoagulation due to diabetic retinopathy, 2 had polypoidal choroidal vasculopathy and 2 central serous choroiditis. Regarding VA results, 77.7% improved or mantained the previous VA. Angiography resolution was observed in 55.5% of the cases (80% with just one PDT session). Average follow up was 10.5 months. Systemic or local complications were not observed. PDT may be useful in the treatment of different types of CNV due to causes other than AMD or high myopia.