Analysis of parameters of the antibacterial treatment of acute otitis media in adults: results of a multicenter study

• Published in: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] Vol. 49; no. 1; p. 30
• Main Authors: Kozlov, S N, Strachunskiĭ, L S, Rachina, S A, Egorova, O A, Paliutin, Sh Kh, Emel'ianova, L A, Dmitrenok, O V, Dobrovol'skaia, T F, Karamysheva, A A, Kuzin, V B, Ortenberg, E A, Chemezov, S A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2004
• Subjects: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents - therapeutic use; Female; Humans; Male; Middle Aged; Otitis Media - drug therapy
• ISSN: 0235-2990

The programme was aimed at audit of the parameters of antibacterial therapy for acute otitis media in adult outpatients in 8 cities of Russia (Smolensk, Volgograd, Ekaterinburg, Yaroslavl, Nizhny Novgorod, Tyumen, Ryazan, Vladivostok). The information sources were the case records. The data from the records were structurally fixed in specially designed individual registration charts for further computer processing. The analysis of the results showed that the real practice of the antibacterial therapy for acute otitis media was not based on a unique approach and did not mainly correspond to the present standards. Ampicillin proved to be preferential, whereas it is known that the drug of choice for such cases is amoxicillin. Antibacterial agents with low activity against the basic pathogens of the infection (doxycycline and others) and high toxicity (co-trimoxazol) were often prescribed, while the recommended up-to-date antibiotics (amoxicillin/clavulanate and others) were prescribed extremely rare or not prescribed at all. Scientifically unreasonable combined antibiotic therapy and prescription of parenteral drugs not rational for the treatment of outpatients were practiced.