Severe thrombocytopenia after heparin therapy in a patient with unstable angina and recent stent implantation
Heparin-induced thrombocytopenia represents a serious side effect of heparin therapy. Immune-mediated platelet activation results in thrombocytopenia, endothelial thrombin release and development of thrombosis, mainly venous. We report the case of a man with a history of coronary artery disease and...
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Published in | Hellenic journal of cardiology Vol. 46; no. 3; p. 242 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
01.05.2005
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Subjects | |
Online Access | Get full text |
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Summary: | Heparin-induced thrombocytopenia represents a serious side effect of heparin therapy. Immune-mediated platelet activation results in thrombocytopenia, endothelial thrombin release and development of thrombosis, mainly venous. We report the case of a man with a history of coronary artery disease and recent stent implantation. This patient developed severe heparin-induced thrombocytopenia type II after low molecular weight heparin administration because of unstable angina which occurred two months after stent implantation. The patient was treated with a new anticoagulant regimen, fondaparinux sodium. There were no complications and platelet counts were restored to normal levels. |
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ISSN: | 1109-9666 |