Myocardial infarction and 5,10-methylenetetrahydro-folate reductase mutation

• Published in: Revista española de cardiologia Vol. 57; no. 5; pp. 476 - 478
• Main Authors: Rodríguez Rodrigo, Francisco J, Medina, Juan, Velásquez, Eddy, Merino, Esther, Delcán, Juan L, Guerrero, Jose E
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.05.2004
• Subjects: Adult; Coronary Angiography; Genotype; Homocysteine - blood; Homocysteine - genetics; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2) - genetics; Mutation; Myocardial Infarction - blood; Myocardial Infarction - enzymology

A 40-year-old woman with previous venous thrombosis in the lower limbs had recurrent myocardial infarction in the early puerperium. The only documented risk factor was an elevated level of plasma homocysteine, associated to a heterozygotic anomaly in the enzyme responsible for its metabolism, 5,10-m...