Myocardial infarction and 5,10-methylenetetrahydro-folate reductase mutation

A 40-year-old woman with previous venous thrombosis in the lower limbs had recurrent myocardial infarction in the early puerperium. The only documented risk factor was an elevated level of plasma homocysteine, associated to a heterozygotic anomaly in the enzyme responsible for its metabolism, 5,10-m...

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Published inRevista española de cardiologia Vol. 57; no. 5; pp. 476 - 478
Main Authors Rodríguez Rodrigo, Francisco J, Medina, Juan, Velásquez, Eddy, Merino, Esther, Delcán, Juan L, Guerrero, Jose E
Format Journal Article
LanguageSpanish
Published Spain 01.05.2004
Subjects
Adult
Coronary Angiography
Genotype
Homocysteine - blood
Homocysteine - genetics
Humans
Male
Methylenetetrahydrofolate Reductase (NADPH2) - genetics
Mutation
Myocardial Infarction - blood
Myocardial Infarction - enzymology
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Summary:A 40-year-old woman with previous venous thrombosis in the lower limbs had recurrent myocardial infarction in the early puerperium. The only documented risk factor was an elevated level of plasma homocysteine, associated to a heterozygotic anomaly in the enzyme responsible for its metabolism, 5,10-methylenetetrahydrofolate reductase. The case and approaches to treatment are discussed.
Bibliography:ObjectType-Article-2
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ISSN:0300-8932
1579-2242