Extrapancreatic tumour-induced hypoglycaemia

A 53-year-old non-diabetic man was admitted with hypoglycaemia, neuroglycopenic symptoms and acromegaloid facial swelling. Serum insulin concentration was suppressed, but the free concentration of insulin-like growth factor (IGF-II) was markedly elevated. CT scan demonstrated a large tumour in the l...

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Bibliographic Details
Published inUgeskrift for læger Vol. 168; no. 5; p. 488
Main Authors Rabøl, Rasmus, Nielsen, Jens Frystyk, Kirkegaard, Preben, Mogensen, Anders Mellon, Johansen, Klaus
Format Journal Article
LanguageDanish
Published Denmark 30.01.2006
Subjects
Diagnosis, Differential
Fibroma - complications
Fibroma - diagnosis
Fibroma - surgery
Hepatectomy
Humans
Hypoglycemia - diagnosis
Hypoglycemia - etiology
Insulin-Like Growth Factor II - analysis
Liver Neoplasms - complications
Liver Neoplasms - diagnosis
Liver Neoplasms - surgery
Male
Middle Aged
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Summary:A 53-year-old non-diabetic man was admitted with hypoglycaemia, neuroglycopenic symptoms and acromegaloid facial swelling. Serum insulin concentration was suppressed, but the free concentration of insulin-like growth factor (IGF-II) was markedly elevated. CT scan demonstrated a large tumour in the liver. The histology showed a benign, solid, fibrous tumour. A hemihepatectomy was performed, and a 3.6 kg tumour was removed. Postoperatively, the blood glucose concentration and the concentration of free IGF-II returned to normal and the acromegaloid facial features disappeared.
ISSN:1603-6824