Cardiolipin antibodies in pregnancy of high risk

Cardiolipin IgG and IgM antibodies (CAb) were studied in 116 cases of high-risk pregnancy. All the women were undergoing examination or treatment in regional perinatal center. CAb occurred more frequently in antenatal fetal death (50%). In blood hypertension, habitual abortions, history of infertili...

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Bibliographic Details
Published inKlinicheskaia meditsina Vol. 77; no. 4; p. 19
Main Authors Karpov, N Iu, Baranov, A A, Shilkina, N P, Nasonov, E L, Aleksandrov, S E, Abaĭtova, N E, Krylov, V L, Lavrinenko, A A, Pushkina, N I
Format Journal Article
LanguageRussian
Published Russia (Federation) 1999
Subjects
Adolescent
Adult
Antibodies, Anticardiolipin - analysis
Biomarkers - blood
Cardiolipins - immunology
Female
Follow-Up Studies
Gestational Age
Humans
Immunoglobulin G - immunology
Immunoglobulin M - immunology
Pregnancy
Pregnancy Outcome
Pregnancy, High-Risk - blood
Pregnancy, High-Risk - immunology
Retrospective Studies
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Summary:Cardiolipin IgG and IgM antibodies (CAb) were studied in 116 cases of high-risk pregnancy. All the women were undergoing examination or treatment in regional perinatal center. CAb occurred more frequently in antenatal fetal death (50%). In blood hypertension, habitual abortions, history of infertility, gestational gestosis, CAb were encountered in 21.4, 20, 20 and 15.2% of cases, respectively. Intrauterine growth retardation was associated with CAb in 33.3% of cases. CAb occurred in pregnant women of different groups who had high uterine vascular resistance. The above findings indicate CAb contribution to genesis of gestational complications in high risk pregnancy.
ISSN:0023-2149