Effect of superphonoelectrophoresis on chorioretinal dystrophy

The effect of a pharmacophysical method superphonophoresis on the course of chorioretinal dystrophy has been studied in 320 patients (640 eyes) with chorioretinal dystrophies treated by an ultrasonic UZT-104 device and a Nion galvanic device. The "superexposure" was phonophoresis of a bipo...

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Bibliographic Details
Published inVestnik oftal'mologii Vol. 115; no. 4; p. 19
Main Authors Gvarishvili, E P, Dushin, N V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1999
Subjects
Adaptation, Ocular - drug effects
Adult
Aged
Aged, 80 and over
Antioxidants - administration & dosage
Blood Flow Velocity - drug effects
Choroid - blood supply
Choroid Diseases - complications
Choroid Diseases - drug therapy
Choroid Diseases - physiopathology
Drug Therapy, Combination
Humans
Iontophoresis
Middle Aged
Phonophoresis
Retinal Degeneration - complications
Retinal Degeneration - drug therapy
Retinal Degeneration - physiopathology
Treatment Outcome
Vasodilator Agents - administration & dosage
Visual Acuity - drug effects
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Summary:The effect of a pharmacophysical method superphonophoresis on the course of chorioretinal dystrophy has been studied in 320 patients (640 eyes) with chorioretinal dystrophies treated by an ultrasonic UZT-104 device and a Nion galvanic device. The "superexposure" was phonophoresis of a bipolar drug 10% dimethylsulfoxide, creating the optimal conditions for penetration of the main agent through tissue barrier. The results (improvement of visual acuity, hemodynamics, trophics, shown by a higher linear rate of the blood flow in the orbital artery and middle cerebral arteries) persisted for up to 12 months, moreover, the rate of cellular and tissue metabolism increased (the time of adaptation to darkness decreased and color sensitivity increased).
ISSN:0042-465X