The role of an overall coronary bed affection in heart remodeling in patients with stenocardia and arterial hypertension

To study a possible role of coronary circulation condition in remodeling heart in ischemic heart disease (IHD) patients with hypertension or without it. The examination (veloergometry, echo-CG and Doppler echocardiography, selective coronaroangiography and left ventriculography) covered 45 hypertens...

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Published inTerapevtic̆eskii arhiv Vol. 74; no. 4; p. 53
Main Authors Dmitriev, V L, Volkova, E G, Levashov, S Iu
Format Journal Article
LanguageRussian
Published Russia (Federation) 2002
Subjects
Angina Pectoris - complications
Angina Pectoris - physiopathology
Coronary Circulation
Coronary Disease - complications
Coronary Disease - physiopathology
Humans
Hypertension - complications
Hypertension - physiopathology
Hypertrophy, Left Ventricular - etiology
Hypertrophy, Left Ventricular - physiopathology
Male
Middle Aged
Stroke Volume
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - physiopathology
Ventricular Remodeling
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Summary:To study a possible role of coronary circulation condition in remodeling heart in ischemic heart disease (IHD) patients with hypertension or without it. The examination (veloergometry, echo-CG and Doppler echocardiography, selective coronaroangiography and left ventriculography) covered 45 hypertensive men with angina of effort functional class III and 69 normotensive patients. Mean age of the patients was 51.8 +/- 1.2 years, duration of the angina 3 to 10 years. Correlation analysis of the data on hypertensive examinees discovered a direct correlation between proportional overall lesion of the coronary arteries, myocardial mass index and left ventricular (LV) index of systolic sphericity, between the sphericity index and myocardial mass index. An inverse correlation--with LV ejection fraction. In anginal patients, coronary circulation is an independent factor influencing LV remodeling. With progression of coronary failure remodeling intensifies. In patients with angina arterial hypertension contributes to the same degree to an increase in the personage of overall affection of the coronary bed, LV systolic sphericity index and index of its myocardial mass, forms an integral, global risk of heart remodelling and, later, heart failure.
ISSN:0040-3660