Clinical case of the month: clostridium difficile colitis

A 55-year-old patient with mant e cels underwent a cytotoxic chemotherapy (D.H.A.P. + Rituximab). During the medullar aplasia related to the third cycle, diarrhoea due to Clostridium difficile arised and relapsed 15 days later despite normal blood counts. This colitis was very severe with pluribacte...

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Bibliographic Details
Published inRevue médicale de Liège Vol. 61; no. 11; pp. 750 - 752
Main Authors Laret, V, Sion, C, Bataille, C, Hustinx, R, Reginster, M
Format Journal Article
LanguageFrench
Published Belgium 01.11.2006
Subjects
Anti-Bacterial Agents - therapeutic use
Clostridium difficile - isolation & purification
Enterocolitis, Pseudomembranous - diagnosis
Enterocolitis, Pseudomembranous - drug therapy
Humans
Immunocompromised Host
Male
Middle Aged
Peritonitis - drug therapy
Peritonitis - microbiology
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Summary:A 55-year-old patient with mant e cels underwent a cytotoxic chemotherapy (D.H.A.P. + Rituximab). During the medullar aplasia related to the third cycle, diarrhoea due to Clostridium difficile arised and relapsed 15 days later despite normal blood counts. This colitis was very severe with pluribacterial peritonitis, but resolved with intensive medical treatment. The incidence, the patient's risk factors, the iatrogenic and nosocomial characters of cl. difficile colitis are discussed.
Bibliography:ObjectType-Article-2
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ISSN:0370-629X