Arthrotec treatment of rheumatoid arthritis

To try arthrotek, a combined drug, in patients with rheumatoid arthritis (RA). 10 RA women aged 30 to 60 years with endoscopically verified minimal affection of gastroduodenal mucosa (not more than 25 hemorrhages and/or 5 erosions) received arthrotek (1 tablet 3 times a day for 3 months). The effica...

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Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 72; no. 1; p. 59
Main Authors Iakushin, S S, Filonenko, S P, Dediunina, R S, Lukina, I M
Format Journal Article
LanguageRussian
Published Russia (Federation) 2000
Subjects
Administration, Oral
Adult
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Arthritis, Rheumatoid - drug therapy
Diclofenac - administration & dosage
Diclofenac - therapeutic use
Drug Combinations
Endoscopy, Digestive System
Female
Gastric Mucosa - drug effects
Gastric Mucosa - pathology
Humans
Middle Aged
Misoprostol - administration & dosage
Misoprostol - therapeutic use
Treatment Outcome
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Summary:To try arthrotek, a combined drug, in patients with rheumatoid arthritis (RA). 10 RA women aged 30 to 60 years with endoscopically verified minimal affection of gastroduodenal mucosa (not more than 25 hemorrhages and/or 5 erosions) received arthrotek (1 tablet 3 times a day for 3 months). The efficacy was judged by changes in the joints and gastroduodenal lesions. The 3-month treatment produced positive changes in the main auricular and gastroduodenal symptoms. Side effects (head ache, diarrhea, sleepiness) disappeared after reducing the day dose to 2 tablets. Arthrotek proved highly effective against RA. It is also a good gastroprotector promoting healing of gastroduodenal erosions.
ISSN:0040-3660