Atrophy of the tympanic membrane in contact with hydroxyapatite prosthesis: physiopathologic approach

The implantation of ossicular replacement prothesis made of dense hydroxyapatite (HA) appears to be a wider method of reconstruction of ossicular chain damaged by suppurative processes or surgery. A review of 19 patients who underwent implantation of HA prosthesis disclosed 4 cases of extrusion and...

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Published inAnales otorrinolaringologicos ibero-americanos Vol. 28; no. 5; p. 513
Main Authors Ramírez Camacho, R, Pinilla Urraca, M, García Berrocal, J R, Vallet-Regí, M
Format Journal Article
LanguageSpanish
Published Spain 2001
Subjects
Atrophy - etiology
Durapatite - adverse effects
Humans
Ossicular Prosthesis - adverse effects
Tympanic Membrane - pathology
Tympanic Membrane - physiopathology
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Summary:The implantation of ossicular replacement prothesis made of dense hydroxyapatite (HA) appears to be a wider method of reconstruction of ossicular chain damaged by suppurative processes or surgery. A review of 19 patients who underwent implantation of HA prosthesis disclosed 4 cases of extrusion and 3 cases of atrophy. When X-ray diffraction analysis of explanted commercially available prosthesis made of dense HA was compared with the results with porous implants and with HS powder employed in the manufacture of both, is suggested that tympanic membrane atrophy could be caused by mechanical and/or chemical factors.
ISSN:0303-8874