Immunoglobulin G kappa [IgG kappa] and IgG lambda paraproteinemia in a child with AIDS and response to highly active antiretroviral therapy

We report an 8-year-old boy with AIDS, extremely elevated serum immunoglobulin G (IgG) concentration and IgG kappa [IgG(kappa)] and IgG lambda [IgG(lambda)] paraproteinemia. This paraproteinemia partially responded to highly active antiretroviral therapy. This case emphasizes the importance of contr...

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Bibliographic Details
Published inClinical and diagnostic laboratory immunology Vol. 12; no. 11; pp. 1331 - 1333
Main Authors Seeborg, Filiz Odabasi, Gay, Hannah, Schmiege, 3rd, Lorenz M, Bernard, David, Shearer, William T
Format Journal Article
LanguageEnglish
Published United States 01.11.2005
Subjects
Acquired Immunodeficiency Syndrome - blood
Acquired Immunodeficiency Syndrome - drug therapy
Acquired Immunodeficiency Syndrome - immunology
Adult
Antiretroviral Therapy, Highly Active
Child
Humans
Immunoglobulin G - blood
Immunoglobulin kappa-Chains - blood
Immunoglobulin lambda-Chains - blood
Male
Paraproteinemias - immunology
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Summary:We report an 8-year-old boy with AIDS, extremely elevated serum immunoglobulin G (IgG) concentration and IgG kappa [IgG(kappa)] and IgG lambda [IgG(lambda)] paraproteinemia. This paraproteinemia partially responded to highly active antiretroviral therapy. This case emphasizes the importance of controlling B-cell activation.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:1071-412X