Update on the pharmacological interactions of systemic antifungal agents

The incidence of systemic fungal infections has increased considerably in the last few decades, however the number of available antifungal agents continues to be reduced. Furthermore, these infections tend to affect patients with severe underlying diseases who are treated with different types of med...

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Bibliographic Details
Published inRevista española de quimioterapia Vol. 12; no. 2; p. 107
Main Authors Viudes, A, Pemán, J, Cantón, E, Ubeda, P, Gobernado, M
Format Journal Article
LanguageSpanish
Published Spain 01.06.1999
Subjects
Amphotericin B - pharmacology
Antifungal Agents - pharmacology
Azoles
Drug Interactions
Flucytosine - pharmacology
Humans
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Summary:The incidence of systemic fungal infections has increased considerably in the last few decades, however the number of available antifungal agents continues to be reduced. Furthermore, these infections tend to affect patients with severe underlying diseases who are treated with different types of medication which may interact with antifungal agents, thus reducing their therapeutic efficacy or increasing their toxicity. In this paper, we discuss the interactions of systemic antifungal agents with other medications and comment on their clinical consequences and the therapeutic approach to adopt in each case.
ISSN:0214-3429